/ Announcement

/ About

Our research teams focus on chronic bone and joint diseases and aim to understand the mechanisms of disabling diseases and to targeted therapies.

Our general approach is based on cohorts, and integrates basic research through the development of murine and cellular models to explore molecular mechanisms and therapeutic targeting.

/ Research topics

Bone

Martine COHEN-SOLAL
Thomas FUNCK-BRENTANO

Exploring the mechanisms of bone fragility by analyzing key molecules involved in bone remodeling and the mode of action of drugs directly implicated in current or innovative treatments.
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Osteoarthritis

Eric HAY
Augustin LATOURTE

Identify new molecules controlling osteo-articular destruction in an inflammatory or mechanical context
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Microcrystal-related diseases

Hang Korng EA
Pascal RICHETTE

Our research on microcrystal-related diseases, including gout, calcium pyrophosphate deposition (CPPD), and basic calcium phosphate, aims to identify molecular and cellular markers that regulate crystal formation, crystal-induced inflammation, and crystal-related comorbidities.
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Tumor & micro environment

Dominique MODROWSKI

Bone metastasis and Biology of Bone Sarcomas are to study how bone factors and bone micro environment could contribute to bone metastasis.
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/ Technical plateforms

Histology

Mylène ZARKA

The BIOSCAR histology core facility specialises in the processing and analysis of mineralised tissues.

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X-ray Imaging

Agnès OSTERTAG

The imaging platform specializes in research on bones and joints, with a strong connection to clinical research.
Our imaging methods help us develop biomarkers. These markers are quantitative tools designed to track structural changes in both pathological and normal bone and joint tissues.

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/ Cohort & biobanks

Cohort & biobanks

Hang Korng EA

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